Prolotherapy works by causing a temporary, low grade inflammation at the injection site, activating fibroblasts to the area, which, in turn,
synthesize precursors to mature collagen and thus reinforce connective tissue. It has been well documented that direct exposure of
fibroblasts to growth factors (either naturally occurring or added) causes new cell growth and collagen deposition. Inflammation creates
secondary growth factor elevation. The inflammatory stimulus of Prolotherapy raises the level of growth factors to resume or initiate a new
connective tissue repair sequence which had prematurely aborted or never started. Animal biopsy studies show ligament thickening,
enlargement of the tendon/bone junction, and strengthening of the tendon or ligament after Prolotherapy injections.
We have found this to be a useful adjunct treatment with no known side effects. We have found this as a good alternative to send off for
cortisone.